Unlocking the Secrets of Polynucleotide Injectables: A Comprehensive Guide

Published by Sarah Spencer on 27 March 2024


  • GOOD FOR: Natural skin rejuvenation for texture and pigmentation
  • STARRING ROLE: Under eye where fillers not suitable
  • REGIME: At least 3 sessions 2-4 weeks apart
  • DOWNTIME: 24-72h
  • OUCH SCALE: 2/5 – numbing cream supplied
  • PRICE: From £600 for course of 3

In the ever-evolving landscape of aesthetic medicine, polynucleotide (PN) injectables have emerged as a revolutionary treatment option, promising to rejuvenate and revitalize the skin. In this comprehensive guide, we'll explore the fascinating world of polynucleotide injectables, covering everything from what they are to the benefits, suitable areas of application on the face, typical injection regimes, and essential aftercare.

What are Polynucleotides?

Polynucleotides are derived from the fundamental building blocks of DNA and RNA. These naturally occurring compounds play a pivotal role in cellular repair and regeneration. In the context of aesthetic medicine, polynucleotide injectables utilize this regenerative power to stimulate the skin's natural healing processes. They are harvested from salmon fish, providing a commercially viable and genetically simialr source of nucleic acids. No fish cells remain after the patented highly purified technology, so they can even be used with patients with fish allergy.

Medical Origins of Polynucleotides:

The medical use of PN can be traced back several decades. Like many other aesthetic medications, PN found applications in the field of wound healing and tissue repair. The regenerative properties of PN were recognized for their ability to accelerate the natural healing processes within the body.

Aesthetic Evolution:

The transition from medical to aesthetic use of PN occurred as researchers and practitioners discovered the potential of these compounds in promoting skin rejuvenation. The aesthetic industry began exploring ways to leverage the regenerative powers of PN to address common concerns related to aging and skin quality.

What are the Benefits of Polynucleotide Injectables?

The benefits of PN injectables are multifaceted. These injections contribute to improved skin elasticity, enhanced hydration, and an overall improvement in skin texture. One of the standout advantages is their ability to boost collagen production, which is crucial for achieving a more youthful and revitalized appearance. Additionally, PN injectables are known for their natural-looking results, making them an appealing option for those seeking subtle yet impactful enhancements.

What Areas of the Face are They Good For?

PN injectables are versatile and can be applied to various areas of the face. These injections are particularly effective in addressing common concerns such as fine lines, wrinkles, and loss of volume. Additionally, specialized applications for the delicate eye area make them an ideal choice for combatting issues like dark circles, under-eye bags, and crow's feet. The adaptability of PN injectables makes them suitable for a wide range of facial enhancements.

Typical Injection Regimes:

The specific injection regime may vary depending on individual needs and desired outcomes, but at least 3 sessions are needed, with maximum results being seen 30-60 days after the final dose. The treatment is minimally invasive, and can be administered with a cannula or needle, with numbing cream supplied initially. Depending on the product used and area treated, the sessions can be 2-4 weeks apart. Each product comes in a 2ml syringe. This is enough to treat both eye areas, about 1/3rd of the face, the neck or the whole décolletage.

Aftercare: Like any injectable, keeping the areas clean in vital to avoid infection. Swelling, redness and bruising are common, but usually short lived. Staying well-hydrated and protecting the treated areas from excessive sun exposure are also key components of effective aftercare.

Conclusion: PN injectables stand at the forefront of non-surgical aesthetic treatments, offering a natural and effective solution for facial rejuvenation. As we've explored, the benefits, versatility, and relatively straightforward aftercare make them an appealing option for individuals seeking to enhance their appearance without the downtime associated with more invasive procedures. For those considering PN injectables, Dr Sarah offers the Mastelli PLINEST range from Dermafocus, the leading company in PN technology since 1986.