At Formation, we take a fundamentally different approach
It is a partial sequence of the body protection compound (BPC) that is naturally discovered in and isolated from human gastric juice
Previously, BPC 157 as an originally anti-ulcer peptide was implemented in inflammatory bowel disease trials [1015], and now multiple sclerosis [16], lethal dose (LD1) could be not achieved [1016]
The dose escalation schedule of these medications also plays a role, with gastrointestinal symptoms often more pronounced during dose increases
L-NAME and BPC 157 regimens and dose application were adjusted according to our previous studies (reviewed Alternatively, to perceive the effect of the given medication itself (without L-NAME), rats received only BPC 157 (total dose 10 g/kg or 10 ng/kg as retrobulbar application in each eye, 1 g/0.1 ml saline/each eye, or 1 ng/0.1 ml saline/each eye) or only saline via retrobulbar application in each eye (0.1 ml/each eye) (as an additional control sham group) at the corresponding time point