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Causes and considerations: Direct taste sensation from the copper-containing complex Post-nasal drip from nasal formulations Transient effect often mitigated with delivery technique adjustments The metallic taste is not typically a clinically meaningful adverse effect, but it can be bothersome enough that patients discontinue therapy

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Cu,Zn-SOD is the primary copper-containing metalloenzyme in eukaryotes and it is enzymatic action was not identified until 1969, when McCord and Fridovich found its ability to dismutate superoxide anion [23]

Bearberry extract contains arbutin, which helps lighten pigmentation and provide a brighter, more even complexion