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128 Not much is known about its physiological role, despite the high OXM- like immunoreactivity in the CNS, particularly in the hypothalamus
They survive low oxygen and high inflammation the exact conditions inside a worn-out joint or damaged disc
For women, the primary interest lies in its influence on melatonin secretion and circadian function both of which decline markedly in menopause and contribute to the sleep disruption that compounds metabolic deterioration in this phase
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