44 Aside from the core features above, individuals with ASD are frequently associated with co-occurring symptoms, including dyskinesia (hypotonia, bradykinesia), speech delay, sleep disorder, gastrointestinal problems, anxiety and epilepsy, which are the most common symptoms in preschool children, while in adolescents and adults, the proportion of depressive symptoms is higher
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However, whether melatonin plays the same role in HI brain injuries is unknown
doi: 10.1074/jbc.M114.588129 28 PatelHAlthubaitiNParmarRYadavNJoshiUTyagiRKet al
It is not simply a structural adjustment but an active, energy-responsive system that continuously remodels the mitochondrial network to preserve genomic integrity, support oxidative phosphorylation, regulate calcium handling, maintain redox balance, and enable adaptive signaling