B12 is non-toxic at any dosage and does not have any negative side effects
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Methods Animals Animal experiments were performed with adherence to all national and local guidelines and regulations, the Guide for the Care and Use of Laboratory Animals 25 , and the ARRIVE guidelines, and with the approval of the Institutional Animal Care and Use Committee at The University of Texas Medical Branch (UTMB)
Dottori L, Pivetta G, Annibale B, Lahner E
Some people are far more likely to run low on B12: Vegans and vegetarians, since B12 comes mainly from animal foods Older adults, because we absorb B12 less efficiently with age People with Crohn's, celiac, or other digestive conditions Anyone who has had gastric bypass or bowel surgery People taking metformin, antacids, or acid reducers long term Heavy alcohol users How B12 injections support weight loss Here is the honest version: B12 is not a fat-burning drug, and a shot will not melt away pounds on its own