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Finally, frequency of GSTP1 aberrant methylation in diffuse large B-cell lymphoma (DLBCL) also led to studies to validate the prognostic impact of such epigenetic alteration in these lymphomas

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The complex translocates to the nucleus, binds androgen response elements on DNA, and modulates gene transcription, promoting protein synthesis, muscle hypertrophy, erythropoiesis, and development/maintenance of male secondary sexual characteristics