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Systematic administration of vitamin E did not show a protective effect in laboratory animals including the inability to attenuate dopamine depletion (Martinovits et al

Severe events that have been reported and contributed to discontinuation include IgE-mediated hypersensitivity in 4% of participants in some trials, with one reported anaphylaxis-like reaction [wong (2008) abstract]

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The authors concluded that GHK-copper may help restore the proliferative potential of epidermal stem cells and increase their potential to repair tissue