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The Lancet (2023) This Phase 2 trial evaluated CagriSema versus semaglutide alone and cagrilintide alone in 92 adults with type 2 diabetes and overweight or obesity on metformin with or without an SGLT2 inhibitor across 17 US sites

Rationale: Elevated GH and IGF-1 support osteoblast proliferation, collagen synthesis, and overall tissue repair capacity

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