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10.1080/19490976.2023.2297860 21 ChungL.OrbergE

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A 2021 review performed by the nonprofit organization Association for Science in Autism Treatment found that the Brain Balance approach lacks sufficient empirical evidence and should therefore be considered a pseudoscientific treatment. The current program is based on contemporary developmental neuroscience and supported by a modern evidence base developed independently of any former contributors, a Brain Balance representative told The Transmitter

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In some embodiments, a formulation described herein, further comprises a gelling agent (e.g., poloxamer 407) and provides release of the therapeutic agent over a period of from about 2 days to about 7 days