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Abbreviations AA Amino acid AGAT L-arginine:glycine amidinotransferase GAMT Guanidinoacetate N -methyltransferase GSH Glutathione (reduced form) GSSG Glutathione disulfide (oxidized glutathione) HPLC High-performance liquid chromatography HSB Hybrid striped bass SBM Soybean meal Authors contributions GW conceived, designed, and supervised this project

In HCC cells, where ACSL4 is overexpressed and is associated with lower overall survival and disease-free survival (DFS) in patients with the disease, ACSL4 also plays a significant role

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