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Because there are therapies with evidence of favourable benefit-to-harm profiles, using therapies with very uncertain evidence of effectiveness is an important opportunity cost in that a potentially effective intervention is not attempted

Looking to bolster sales, Marlboro called upon the prowess of Leo Burnett, a titan of 20th century advertising, to help make smoking Marlboro filtered cigarettes more attractive to men

A medium-sized cigar will last long enough and pack enough flavor to be enjoyed by most smokers

Exceeding this limit can blow the fuse or damage the socket

PM levels can sometimes be higher in enclosed buildings than outdoors because PM concentrations are less diluted indoors (Umweltbundesamt 2014)