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Systematic phenotyping and characterization of the 3xTg-AD mouse model of Alzheimers disease

As previously reported by our laboratory and others, both AD and mild cognitive impairment (MCI) brains have significantly decreased levels of antioxidant enzymes, making the brain more vulnerable to A(142)-induced toxic effects [10]

Human cytosolic GSTs belong to the alpha, zeta, theta, mu, pi, sigma, and omega classes, while six isozymes belonging to classes I, II, and IV of the MAPEG superfamily are known to exist

Furthermore, despite their low calorie content, they contain moderate amounts of protein and fiber