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doi: 10.1016/j.jaut.2009.11.006, 61

Surgeons like Dr

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Disruption of these pathways, through enhanced uptake, excessive ferritin degradation, or reduced FPN activity, elevates intracellular Fe 2 levels and drives ferroptotic susceptibility

Lotiglipron was discontinued in 2023 owing to unfavourable pharmacokinetic drug-drug interaction data from two Phase I studies and to elevated transaminases indicative of liver dysfunction in a subset of patients 24