[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Subramanian V, Rothenberg A, Gomez C, Cohen AW, Garcia A, Bhattacharyya S, et al
Extracts from insect (53, 62) and mammalian cells (53, 62) transfected with adiponutrin possess functional TAG lipase activity that requires the active site serine (G X S X G motif) when assayed in vitro (62)
Vitamin B12 deficiency has been associated with peripheral neuropathy and even cognitive deficits, especially in older adults and those with HIV/AIDS, where it supports nerve function and assists in the maintenance of myelin sheath integrity
Most reported symptoms lack robust causal evidence and may reflect coincidental findings or underlying conditions
Endogenous causes (medical conditions) When B12 is elevated without supplementation , it can indicate that the body is releasing stored B12 from damaged tissues, producing excess B12-binding proteins, or failing to clear B12 normally