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Dual regulation of Ca 2+ -dependent glutamate release from astrocytes: vesicular glutamate transporters and cytosolic glutamate levels

Actual medications may vary depending on the prescribing provider, pharmacy, and applicable regulations

All subjects were informed of the use of their renal biopsy samples, and written informed consent was obtained

Dysregulation of the kynurenine pathway, as evidenced by low kynurenine levels has been linked to cognitive impairments such as brain fog and memory issues, which are commonly reported in both ME/CFS and FM (Groven et al., 2021

Acknowledgements The authors thank Emelia Tremblay and Mazie Gordon at the University of Maine, for their help with microbial lab work, Benjamin and Timothy Hunt at the University of Maine for their work reviewing literature on GR converting genes, and Scott Leonard at Oregon State University for analyzing urine samples for nitrile content