In this review, we examine how GSH restrains both executioner-driven cell death pathways, including apoptosis, necroptosis, and pyroptosis, which are mediated by defined signaling cascades and dedicated effector proteins, and metabolism-centered forms of cell death, including ferroptosis and cuproptosis, which arise from overwhelming lipid peroxidation and proteotoxic stress, respectively
Deters, B
Liver disease NAFLD is widely assumed as the most common chronic liver disease, and the interaction between lipid metabolism disorders and the resulting inflammatory response can jointly promote the occurrence and development of NAFLD
For instance, the reverse-mode NNT that consumes NADPH to support NADH and ATP productions in contrast to the conventional view has not been reported with respect to cancer
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