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As diabetes progresses, advancing apoptosis of the nitrergic nerves in the major pelvic ganglion (MPG) generally follows, attributed to severe oxidative stress [117,118]

Effective solutions include culturally sensitive recruitment strategies, decentralized or hybrid trial models, and partnerships with local health leaders

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failed to show an improvement in semen parameters, sperm survival, or pregnancy rates after the administration of high-doses of Vitamin C and E for 56 days.[40] Despite that, more recent studies have conveyed a beneficial effect for antioxidant regimens-containing Vitamin C in different clinical scenarios