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In the fourth and last stage of B12 deficiency, clinical manifestations are experienced by the individual including macrocytic anemia (a form of anemia in which red blood cells are larger than usual, hence the term macro) and, if left untreated, irreversible neurological damage

V.HongJ.KimW.et al (2018)

[16] [17] Funcin [editar] En el estado reducido, el grupo tiol de la cistena es capaz de donar un equivalente de reduccin (H + + e - ) a otras molculas inestables, tales como las especies reactivas de oxgeno

The United States Pharmacopeia, & the National Formulary