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Impaired mitophagy and/or ferritinophagy may be important factors in abnormal metal accumulation, but considering the differences in protein levels in different types of cells during aging, the interrelationship might be very complex, or it these relationships may be mutually reinforcing and causal [189]

doi: 10.3390/cells9122648 34 DhanasekaranRDeutzmannAMahauad-FernandezWDHansenASGouwAMFelsherDW

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