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Graphical abstract Highlights Emerging phytotherapeutics like Aloe vera and Mahonia aquifolium showed marked inhibition of pro-inflammatory cytokines such as IL-17 and IL-23 in preclinical models

Researchers should check whether the COA is batch-specific, whether the compound name matches the listing, whether the method fields are clear, and whether the results are tied to the same lot

Sample Preparation Whole blood samples should be diluted 20-fold with water prior to the assay (n = 20)

The assortment is rich in verified natural extracts, plant stem cells, specifically active peptides, and even precious metals, such as gold, which are selected for their proven regenerative, nourishing, and protective properties

Bilirubin, an endogenous antioxidant that affects p53 protein and its downstream apoptosis/autophagy-related genes in LS180 and SW480 cell culture models of colorectal cancer