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IHC synapses can immediately and permanently degenerate after noise exposure, independent of hair cell loss, whereas the cell bodies and central projections of cochlear neurons can survive for months to years, providing an extended therapeutic window for improving afferent input through synapse regeneration

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In turn, this could cause swelling to be noticeably present from the elbow down into the forearm

DSIP is a low-molecular-weight amphiphilic nonapeptide the selective membrane that separates circulating blood from brain tissue