31 As compared with vehicle-treated cells, erastin treatment caused much increase in MDA in SKOV3 and OVCA429 cells, but not in SKOV3 Era-R and OVCA429 Era-R cells (Fig
This phenomenon not only exists in glucose metabolism, but also in glutamine metabolism, where the level of glutamine in MET-induced tumors is nearly doubled, and further research has found that glutamine catabolic metabolism is increased in MYC-induced tumors, while glutamine synthesis is increased in MET-induced tumors (83)
A worldwide multicentre evaluation of the influence of deterioration or improvement of acute kidney injury on clinical outcome in critically ill patients with and without sepsis at ICU admission: Results from the intensive care over nations audit
During energy production via the catabolic oxidative phosphorylation (OXPHOS) pathway, mitochondria produce reactive oxygen species (ROS) that are highly reactive chemicals formed from diatomic oxygen (O 2 )
High-dose vitamin D3 supplementation ameliorates renal fibrosis by vitamin D receptor activation and inhibiting TGF-1/Smad3 signaling pathway in 5/6 nephrectomized rats