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Full methodological details of BE OPTIMAL (ClinicalTrials.gov: NCT03895203) and BE COMPLETE (NCT03896581) are reported in the primary manuscripts, including key inclusion and exclusion criteria

In contrast to PDGF-BB, in diabetic wounds, induced by alloxan application, BPC 157 largely promoted mature collagen in granulation tissue (Seveljevic-Jaran et al., 2006) (note, previously, BPC 157 healed alloxan-induced gastric lesions in rats (Petek et al., 1999))

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