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The rest, like Hiram Pierce, took the so-called "short cut" -- a ship to Panama, a sweltering walk or mule ride across the malaria-riddled isthmus, and then a steamer to San Francisco -- the gateway to the goldfields

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"But they should review this with their doctor every year to see if they need to make changes to their dose or even whether they need to continue taking it." Other situations require short-term drug therapy, such as for 14 days to six weeks after a knee or hip replacement to prevent DVT

That was the arc when they brought it over to AMC