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Vitamin B12 injections are primarily utilized to treat or prevent a deficiency of this vitamin, which is particularly prevalent among older adults due to age-related changes in nutrient absorption

Depletion of TAMs results in the inhibition of tumor angiogenesis, whereas reconstitution of TAMs promotes angiogenesis in murine cancer models [233, 234]

Clinical translational research shows that in a Phase II clinical trial of newly diagnosed high-risk diffuse large B-cell lymphoma (DLBCL) (n=100), oral HDAC inhibitor Tucidinostat (20 mg per dose) in combination with the R-CHOP regimen achieved an 86% complete response rate (91)