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H.YatesJ

Indeed, several glutathione transporters have been identified, including in the tonoplast [81,82], the mitochondrial inner membrane [83], the plastid inner envelope [84], and the plasma membrane [85,86]

Administration of irbesartan reduces the level of inflammatory mediators and reverses Ang II-induced depressive-like behaviors as manifested by decreased immobility times in the modified forced swim test (MFST) and the TST (100)

Zhao, P

Although repurposing existing drugs offers a cost-effective and time-efficient alternative for identifying new therapies, their effective concentrationsmeasured as the half-maximal inhibitory concentration (IC50)often exceed the maximum safe plasma levels in humans, creating a major barrier to clinical application