Here, we found that regional comparisons yielded more significant results than when comparing disease conditions
The enzyme PiGSTT1 was shown to be a glutathione peroxidase highly active with organic hydroperoxide substrates like 9( S )-hydroperoxy-(10 E ,12 Z ,15 Z )-octadecatrienoic acid that is synthesized in potato during infection by P
Rizzo AN, Haeger SM, Oshima K, Yang Y, Wallbank AM, Jin Y, Lettau M, McCaig LA, Wickersham NE, McNeil JB, Zakharevich I, McMurtry SA, Langout-Astri CJ, Kopf KW, Voelker DR, Hansen KC, Shaver CM, Kerchberger VE, Peterson RA, Kuebler WM, Ochs M, Veldhuizen RA, Smith BJ, Ware LB, Bastarache JA, Schmidt EP
Cunningham GR, et al
Notably, perturbation of mitochondrial dynamics modulates this vulnerability: deletion of the fission regulator dynamin-related protein 1 (Drp1) prolongs m maintenance and confers resistance to ferroptotic death [103], whereas ferroptotic signaling is associated with Drp1 activation and mitochondrial fragmentation