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This effect appears to be reversible: When mesalamine was substituted for sulfasalazine, semen quality returned to normal

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Regulation of blood flow and nitric oxide (NO) pathways: BPC-157 has been shown to influence the production and activity of nitric oxide, a signaling molecule involved in various physiological processes

The absence of effects on IGF-1, glucose metabolism, and tissue growth reduces concerns about long-term hormonal consequences, but prudent medical oversight remains appropriate for any extended peptide use