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144 The NLRP3 inflammasomes activation and its interplay with the complement and coagulation systems are of particular interest

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In addition, IgAN patients show a decreased relative abundance of Bifidobacterium , which negatively correlates with proteinuria and hematuria levels, suggesting that a reduction in Bifidobacterium abundance is associated with IgAN severity [141]

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The needle is then secured in place with a piece of tape or bandage, and the IV drip is started