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Thus, many key intracellular signaling events discovered in mice are reproducible in human hepatocytes suggesting that common mechanisms are in play during progression of APAP-induced liver injury

In a mouse experiment, researchers found that mice with an activated TP53 gene exhibited both increased tumor resistance and early aging traits, indicating the complex role of TP53 in cellular function [205]

10.1016/j.semcdb.2017.06.010 200 Sardon PuigL.Valera-AlberniM.CantC.PillonN

If these techniques are unable to distinguish MEVs from other possible co-isolates or suspended pollutants, it is advised that the concentrations for upstream separation operations be reported as particle or EP concentration rather than MEV concentration [239]

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