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Seiwerth et al., 2014

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Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice

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Kupryszewski, et al

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While KPV can reduce intestinal inflammation that contributes to permeability, BPC-157's direct effects on tight junction proteins and epithelial cell regeneration make it more effective for addressing the structural aspects of leaky gut

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