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Proton pump inhibitors increase incidence of nonsteroidal anti-inflammatory drug-induced small bowel injury: A randomized, placebo-controlled trial

Compliance Monitoring Implement strategies to monitor and ensure the subject's compliance with the prescribed dosage regimen, such as participant diaries, regular follow-up visits, and periodic assessments of the remaining spray volume

These may include excessive thirst, skin conditions, blurry vision, abdominal cramps, nausea, vomiting, and increased risk of severe side effects for individuals with existing health conditions

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