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Form: Capsules (for research use only) Target: Nicotinamide N-methyltransferase (NNMT) inhibitor Suggested Application: Preclinical or in vitro metabolic studies Storage: Preserve in a cool, dry environment away from direct light 1

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Non-canonical GH-GHR intracellular signaling is typically independent of JAK2, and involves recruitment of Src family non-receptor tyrosine kinases (45), stimulation of phospholipase C (PLC) and via cytosolic calcium flux from organelles, activation of protein kinase C (PKC) (47)