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2 Smurf1 promotes PDK1 neddylation at K163

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The PCOS model was established through daily subcutaneous injections of dehydroisoandrosterone (DHEA, 60 mg/kg, LKT Laboratories) over a period of 20 days [20]

IGF-1 LR3 is often utilized as a model compound to explore how IGF-1 receptor activation impacts cellular aging mechanisms

Taken together, anti-apoptotic effects of PKC are associated with its ability to regulate the expression of anti-apoptotic and pro-apoptotic factors, a mechanism that cannot be achieved in mature erythrocytes