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and 5 p.m.), with the circadian rhythm maintained even during different stages of lactation [7, 17, 47]

We believe that the low quality shown during summer is not due to a photoperiod seasonal effect, as some of the parameters analyzed presented better results during spring, which is a nonoptimal reproductive season for sheep species at our latitude

As mentioned above, NAC is the go-to treatment for paracetamol overdose

These may be costly and time-consuming, without the guarantee of desired results

The following relevant parameters were determined where possible: area under the concentration-time curve from time zero to the last time point (AUCo-iast) or extrapolated to infinity (AUCo- ), C ma x concentration in plasma extrapolated to time zero (Co), terminal elimination half-life (tj 2), volume of distribution (Vd), and clearance (CL)