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The reported adverse reactions following parenteral administration of vitamin B12 include: Generalized : Anaphylaxis and death Cardiovascular : Pulmonary edema and congestive cardiac/heart failure during early treatment

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But shots given under the skin might need to be done more often because they absorb more slowly. Its key for doctors to adjust treatment plans based on each patients needs

Rhonda Patrick adds: "NAD+ precursors like NMN increase levels, aiding DNA repair and energykey for anti-aging."[34] She suggests stacking with NNMT inhibitors for sustained effects