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[DOI] [PubMed] [Google Scholar] 15.Marsh LM, Cakarova L, Kwapiszewska G, von Wulffen W, Herold S, Seeger W, Lohmeyer J

NAD acts as a central coenzyme in metabolic reactions that convert nutrients into ATP

Given the central role of GPX4 in suppressing lipid peroxidation, these findings further suggest that Prx6 may exert substantial influence on ferroptosis-related pathologies through its regulation of GPX4 expression