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Ello es as ya que la enzima que "reduce" el tripptido a partir de su forma oxidada, la glutatin reductasa, es constitutivamente activa e inducible en situaciones de estrs oxidativo

Duzel A, Vlainic J, Antunovic M, Malekinusic D, Vrdoljak B, Samara M, Gojkovic S, Krezic I, Vidovic T, Bilic Z, Knezevic M, Sever M, Lojo N, Kokot A, Kolovrat M, Drmic D, Vukojevic J, Kralj T, Kasnik K, Siroglavic M, Seiwerth S, Sikiric P

The presence of one doesn't stimulate the other

Table 3 demonstrates plant-derived bioactive compounds/extracts known for their in vivo anti-hyperthyroidism activity

The majority of existing research remains limited to in vitro cellular assays and relies primarily on indirect markers, including GPX4 expression changes or the use of pharmacological inhibitors, to infer mechanistic pathways