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Garlic plants ( Allium sativum ) produce volatile organosulfur compounds, such as diallyl thiosulfinate (allicin) and diallyl polysulfanes, which are known for their antimicrobial, antiviral, anticancer, anti-inflammatory and immunomodulatory effects ( Allicin is a thiol-reactive compound, which reacts with Cys thiols via thiol-disulfide exchange reactions, leading to S -thioallylations of proteins ( S -thioallylations of redox-sensitive Cys residues in proteins were identified in the proteome of human Jurkat cells, Escherichia coli , Staphylococcus aureus , and Bacillus subtilis ( S -thioallylated proteins were identified 10 min after allicin treatment, including highly abundant cytoskeleton proteins, HSP90 chaperones, translation elongation factors and glycolytic enzymes

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