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Selected References United States Pharmacopeia

doi: 10.1038/cddis.2012.183

While peptides are not risk-free and should always be used under qualified medical supervision, they are typically designed to support specific biological functions rather than dramatically altering hormone levels

The results showed that different linkers did not have a remarkable influence on the in vitro binding affinity of MDM2, while positively charged residues produced a significant enhancement in cell uptake and targeted capability in cellular reporter assay, indicating that positive charge is crucial for achieving cell viability using WT-p53 sequence-based stapled peptides

PMID 19812240