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Low vitamin B12 levels are more common than you might think

Meanwhile, the vitamin B component helps increase energy levels and may improve overall metabolic function, which can enhance calorie burning

2 Grip Strength and Exercise Endurance in Aged Mice Dimet-Wiley et al., Scientific Reports (2024) This study compared 5-Amino-1MQ treatment, voluntary wheel-running exercise (PoWeR), and combined treatment in aged C57BL/6J mice

The mechanisms do not appear to contradict each other, and some researchers have speculated that combining them could address both appetite and direct fat cell metabolism