Lipid oxidation products (in particular aldehydes such as MDA) can modify the biophysical properties of cell membranes
Unlike B12 deficiency, there is no specific treatment to reduce elevated levels, nor is this usually necessary, as high B12 is not directly toxic
These three mRNAs collectively encode the G6PD isoform a (545 amino acids) and isoform b (515 amino acids) enzymes
Moreover, uracil, n-oleoylethanolamine, asymmetric (ADMA) and symmetric (SDMA) dimethylarginines (protein degradation residues), palmitoylglycerol (active metabolite) and pseudouridine (nucleotide metabolism) were depleted in T4 only, whereas -muricholic acid (bile acid) was depleted in T5
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