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These are examples of what is reported, not a recommendation

Although our measurements were not region-specific, high-dose paraxanthine augmented BDNF levels more than caffeine, suggesting a dose-dependent effect of paraxanthine, regardless of age

Senescence Reversal: It targets the "senescence-associated secretory phenotype" (SASP), shifting chondrocytes from a catabolic state to an anabolic state