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Materials are distributed exclusively for research mandates within a designated facility

The release of 5-HT remains unchanged in IBS patients, but the decreased expression of SERT may impair the uptake of 5-HT, which increases the availability of 5-HT in the mucosa, enhancing reflex activity and triggering IBS-D

This energy sparing effect can be used to reduce the metabolizable energy content in the feed to achieve additional cost saving

These findings highlighted the importance of host factors such as granuloma structure and immune environment in determining the efficacy of JAK blockers [14]