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Moreover, these effects seem to be dose-dependent, at high concentrations of nicotine, osteoblast-like cells demonstrate decreased proliferation and impaired collagen synthesis 93 , whereas at low levels these cells are stimulated 34

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The FDA is actively considering regulations to reduce cigarette nicotine levels to non-addictive amounts

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Just under two-thirds of those who were aware of e-cigarettes believed them to be harmful and to contain chemicals