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Randomized phase III study of canfosfamide in combination with pegylated liposomal doxorubicin compared with pegylated liposomal doxorubicin alone in platinum-resistant ovarian cancer

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The possible mechanism of actions of angiogenesis inhibitors on tumor blood vessels can be broadly classified into three categories: (a) vessel depletion, (b) vessel normalization, and (c) immune activation (Fig