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The readers are encouraged to consult several recent reviews of specific topics, and some are cited in this article

Several factors have contributed to this challenge, including: Increased intake of energy-dense foods high in sugars and fat

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eye cream study (which outperformed both vitamin K and vitamin C in periorbital wrinkle reduction) round out the photo-aging evidence base 13 14

Free radicals generated by ultraviolet radiation, pollution, and other environmental stressors cause oxidative damage to cellular structures, including DNA, proteins, and lipids that maintain healthy skin function