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Check homocysteine (should be under 9) and MCV (should be 80-92) instead to detect cellular deficiency, even when serum B12 appears normal

The oxidative stress was then induced by treating the cells with increasing concentrations of tert-butyl hydroperoxide (tBuOOH) for 24 h

The TGR inhibitor demonstrating greatest efficacy in treating infected mice, 2 , was also studied after oral administration: 2 (200 mg/kg p.o.) gave plasma concentrations of 0.71, 0.77, and 0.40 M at 30, 60, and 120 min, respectively (Supplementary Table 19)