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In addition to supporting blood vessel health, L-arginine participates in protein metabolism, immune function, and other biochemical pathways that contribute to overall health and wellness

10.1523/JNEUROSCI.3728-09.2009 [DOI] [PMC free article] [PubMed] [Google Scholar] Carter AJ, OConnor WT, Carter MJ, Ungerstedt U (1995) Caffeine enhances acetylcholine release in the hippocampus in vivo by a selective interaction with adenosine A1 receptors

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This makes it particularly effective for individuals suffering from chronic joint pain, arthritis , or sports-related ligament injuries like sprains or strains